YNR058W

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Systematic name YNR058W
Gene name BIO3
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:734291..735733
Primary SGDID S000005341


Description of YNR058W: 7,8-diamino-pelargonic acid aminotransferase (DAPA), catalyzes the second step in the biotin biosynthesis pathway; BIO3 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis[1]




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Community Commentary

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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [2] [3]


Other

Gene Origin

Horizontally transferred from gamma proteobacteria [4] [5]





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References

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  1. Phalip V, et al. (1999) Characterization of the biotin biosynthesis pathway in Saccharomyces cerevisiae and evidence for a cluster containing BIO5, a novel gene involved in vitamer uptake. Gene 232(1):43-51 SGD PMID 10333520
  2. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  3. submitted by Viktor Boer on 2003-07-25
  4. Hall C, et al. (2005) Contribution of horizontal gene transfer to the evolution of Saccharomyces cerevisiae. Eukaryot Cell 4(6):1102-15 SGD PMID 15947202
  5. submitted by Charles Hall on 2006-06-09

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