YNL157W

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Systematic name YNL157W
Gene name IGO1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:340352..340858
Primary SGDID S000005101


Description of YNL157W: Protein required for initiation of G0 program; prevents degradation of nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway; phosphorylated by Rim15p; GFP protein localizes to the cytoplasm and nucleus; similar to Igo2p[1][2]




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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Talarek N, et al. (2010) Initiation of the TORC1-regulated G0 program requires Igo1/2, which license specific mRNAs to evade degradation via the 5'-3' mRNA decay pathway. Mol Cell 38(3):345-55 SGD PMID 20471941

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