YMR304W

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Systematic name YMR304W
Gene name UBP15
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:874987..878679
Primary SGDID S000004920


Description of YMR304W: Ubiquitin-specific protease involved in protein deubiquitination; catalytic activity regulated by an N-terminal TRAF-like domain and and C-terminal sequences; physically interacts with anaphase-promoting complex/cyclosome (APC/C) activator, Cdh1p; forms a complex with AAA peroxins Pex1p and Pex6p[1][2][3]




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References

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  1. Bozza WP and Zhuang Z (2011) Biochemical Characterization of a Multidomain Deubiquitinating Enzyme Ubp15 and the Regulatory Role of Its Terminal Domains. Biochemistry () SGD PMID 21710968
  2. Debelyy MO, et al. (2011) Ubp15p, a ubiquitin hydrolase associated with the peroxisomal export machinery. J Biol Chem 286(32):28223-34 SGD PMID 21665945
  3. Layfield R, et al. (1999) Chemically synthesized ubiquitin extension proteins detect distinct catalytic capacities of deubiquitinating enzymes. Anal Biochem 274(1):40-9 SGD PMID 10527495

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