YMR127C

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Systematic name YMR127C
Gene name SAS2
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:523345..522329
Primary SGDID S000004734


Description of YMR127C: Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family[1][2]




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References

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  1. Osada S, et al. (2001) The yeast SAS (something about silencing) protein complex contains a MYST-type putative acetyltransferase and functions with chromatin assembly factor ASF1. Genes Dev 15(23):3155-68 SGD PMID 11731479
  2. Shia WJ, et al. (2005) Characterization of the yeast trimeric-SAS acetyltransferase complex. J Biol Chem 280(12):11987-94 SGD PMID 15659401

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