YMR079W

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Systematic name YMR079W
Gene name SEC14
Aliases PIT1
Feature type ORF, Verified
Coordinates Chr XIII:424989..426059
Primary SGDID S000004684


Description of YMR079W: Phosphatidylinositol/phosphatidylcholine transfer protein; involved in regulating PtdIns, PtdCho, and ceramide metabolism, products of which regulate intracellular transport and UPR; functionally homologous to mammalian PITPs[1][2][3]




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References

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  1. Mousley CJ, et al. (2008) Trans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast. Mol Biol Cell 19(11):4785-803 SGD PMID 18753406
  2. Schnabl M, et al. (2003) Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover. Eur J Biochem 270(15):3133-45 SGD PMID 12869188
  3. Yanagisawa LL, et al. (2002) Activity of specific lipid-regulated ADP ribosylation factor-GTPase-activating proteins is required for Sec14p-dependent Golgi secretory function in yeast. Mol Biol Cell 13(7):2193-206 SGD PMID 12134061

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