YMR048W

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Systematic name YMR048W
Gene name CSM3
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:366981..367934
Primary SGDID S000004651


Description of YMR048W: Replication fork associated factor, required for stable replication fork pausing; component of the DNA replication checkpoint pathway; required for accurate chromosome segregation during meiosis[1][2][3][4]




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References

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  1. Bando M, et al. (2009) Csm3, Tof1, and Mrc1 form a heterotrimeric mediator complex that associates with DNA replication forks. J Biol Chem 284(49):34355-65 SGD PMID 19819872
  2. Calzada A, et al. (2005) Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork. Genes Dev 19(16):1905-19 SGD PMID 16103218
  3. Mohanty BK, et al. (2006) The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to control replication termination of Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 103(4):897-902 SGD PMID 16418273
  4. Rabitsch KP, et al. (2001) A screen for genes required for meiosis and spore formation based on whole-genome expression. Curr Biol 11(13):1001-9 SGD PMID 11470404

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