YLR452C

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Systematic name YLR452C
Gene name SST2
Aliases
Feature type ORF, Verified
Coordinates Chr XII:1041366..1039270
Primary SGDID S000004444


Description of YLR452C: GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family[1][2][3]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [4] [5]





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References

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  1. Apanovitch DM, et al. (1998) Sst2 is a GTPase-activating protein for Gpa1: purification and characterization of a cognate RGS-Galpha protein pair in yeast. Biochemistry 37(14):4815-22 SGD PMID 9537998
  2. Siderovski DP, et al. (1996) A new family of regulators of G-protein-coupled receptors? Curr Biol 6(2):211-2 SGD PMID 8673468
  3. Siekhaus DE and Drubin DG (2003) Spontaneous receptor-independent heterotrimeric G-protein signalling in an RGS mutant. Nat Cell Biol 5(3):231-5 SGD PMID 12598904
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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