YLR081W
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| Systematic name | YLR081W |
| Gene name | GAL2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:290212..291936 |
| Primary SGDID | S000004071 |
Description of YLR081W: Galactose permease, required for utilization of galactose; also able to transport glucose[1][2][3]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Multiple Knockout Strains
Strain Background: CEN.PK2-1C
Genotype: EBY4000 (hxt)
Together with: HXT15, MPH2, HXT7, HXT6, HXT3, HXT13, HXT10, MAL11, HXT4, HXT1, HXT5, HXT12, HXT8, HXT9, HXT16, MPH3, HXT2, HXT14, HXT17, HXT11
Phenotype(s): Viable
, Conditionally inviable when on glucose medium
The complete hxt null strain (EBY4000) is unable to take up hexoses and to grow on them. It is well suited to express and characterize heterologous glucose transporters. [4] [5]
Protein Details
Protein Function/Process
The Gal2p galactose transporter is one of four Hxt transporters (Hxt4p, Hxt5p, Hxt7p, Gal2p) able to take up xylose [6] [5]
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References
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- ↑ Kasahara T and Kasahara M (2000) Three aromatic amino acid residues critical for galactose transport in yeast Gal2 transporter. J Biol Chem 275(6):4422-8 SGD PMID 10660614
- ↑ Maier A, et al. (2002) Characterisation of glucose transport in Saccharomyces cerevisiae with plasma membrane vesicles (countertransport) and intact cells (initial uptake) with single Hxt1, Hxt2, Hxt3, Hxt4, Hxt6, Hxt7 or Gal2 transporters. FEMS Yeast Res 2(4):539-50 SGD PMID 12702270
- ↑ Rodriguez C and Flores C (2000) Mutations in GAL2 or GAL4 alleviate catabolite repression produced by galactose in Saccharomyces cerevisiae. Enzyme Microb Technol 26(9-10):748-755 SGD PMID 10862881
- ↑ Wieczorke R, et al. (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8 SGD PMID 10618490
- ↑ 5.0 5.1 submitted by Eckhard Boles on 2003-03-17
- ↑ Hamacher T, et al. (2002) Characterization of the xylose-transporting properties of yeast hexose transporters and their influence on xylose utilization. Microbiology 148(Pt 9):2783-8 SGD PMID 12213924
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