YJL179W

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Systematic name YJL179W
Gene name PFD1
Aliases GIM6
Feature type ORF, Verified
Coordinates Chr X:88787..89116
Primary SGDID S000003715


Description of YJL179W: Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin[1][2]




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References

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  1. Siegers K, et al. (1999) Compartmentation of protein folding in vivo: sequestration of non-native polypeptide by the chaperonin-GimC system. EMBO J 18(1):75-84 SGD PMID 9878052
  2. Vainberg IE, et al. (1998) Prefoldin, a chaperone that delivers unfolded proteins to cytosolic chaperonin. Cell 93(5):863-73 SGD PMID 9630229

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