YJL013C
(Redirected from S000003550)
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Systematic name | YJL013C |
Gene name | MAD3 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr X:411040..409493 |
Primary SGDID | S000003550 |
Description of YJL013C: Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover[1][2]
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References
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- ↑ Burton JL and Solomon MJ (2007) Mad3p, a pseudosubstrate inhibitor of APCCdc20 in the spindle assembly checkpoint. Genes Dev 21(6):655-67 SGD PMID 17369399
- ↑ Hardwick KG, et al. (2000) MAD3 encodes a novel component of the spindle checkpoint which interacts with Bub3p, Cdc20p, and Mad2p. J Cell Biol 148(5):871-82 SGD PMID 10704439
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