YGR289C
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| Systematic name | YGR289C |
| Gene name | MAL11 |
| Aliases | AGT1, MALT |
| Feature type | ORF, Verified |
| Coordinates | Chr VII:1075813..1073963 |
| Primary SGDID | S000003521 |
Description of YGR289C: Inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; broad substrate specificity that includes maltotriose; required for isomaltose utilization[1][2][3][4][5]
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Contents
Community Commentary
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Alleles, Strains, and Phenotypes
Multiple Knockout Strains
Strain Background: CEN.PK2-1C
Genotype: EBY4000 (hxt)
Together with: HXT15, MPH2, HXT7, HXT6, HXT3, HXT13, HXT10, HXT4, HXT1, HXT5, HXT12, HXT8, HXT9, HXT16, MPH3, GAL2, HXT2, HXT14, HXT17, HXT11
Phenotype(s): Viable
, Conditionally inviable when on glucose medium
The complete hxt null strain (EBY4000) is unable to take up hexoses and to grow on them. It is well suited to express and characterize heterologous glucose transporters. [6] [7]
DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [8] [9]
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References
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- ↑ Alves SL Jr, et al. (2008) Molecular analysis of maltotriose active transport and fermentation by Saccharomyces cerevisiae reveals a determinant role for the AGT1 permease. Appl Environ Microbiol 74(5):1494-501 SGD PMID 18203856
- ↑ Charron MJ, et al. (1986) Structural and functional analysis of the MAL1 locus of Saccharomyces cerevisiae. Mol Cell Biol 6(11):3891-9 SGD PMID 3025617
- ↑ Cheng Q and Michels CA (1991) MAL11 and MAL61 encode the inducible high-affinity maltose transporter of Saccharomyces cerevisiae. J Bacteriol 173(5):1817-20 SGD PMID 1999393
- ↑ Han EK, et al. (1995) Characterization of AGT1 encoding a general alpha-glucoside transporter from Saccharomyces. Mol Microbiol 17(6):1093-107 SGD PMID 8594329
- ↑ Teste MA, et al. (2010) Characterization of a New Multigene Family Encoding Isomaltases in the Yeast Saccharomyces cerevisiae, the IMA Family. J Biol Chem 285(35):26815-24 SGD PMID 20562106
- ↑ Wieczorke R, et al. (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8 SGD PMID 10618490
- ↑ submitted by Eckhard Boles on 2003-03-17
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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