YGR092W

From SGD-Wiki
(Redirected from S000003324)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YGR092W
Gene name DBF2
Aliases
Feature type ORF, Verified
Coordinates Chr VII:668189..669907
Primary SGDID S000003324


Description of YGR092W: Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis; also plays a role in regulating the stability of SWI5 and CLB2 mRNAs[1][2][3][4]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [5] [6]





<protect>

References

See Help:References on how to add references

  1. Frenz LM, et al. (2000) The budding yeast Dbf2 protein kinase localises to the centrosome and moves to the bud neck in late mitosis. J Cell Sci 113 Pt 19():3399-408 SGD PMID 10984431
  2. Toyn JH and Johnston LH (1994) The Dbf2 and Dbf20 protein kinases of budding yeast are activated after the metaphase to anaphase cell cycle transition. EMBO J 13(5):1103-13 SGD PMID 8131744
  3. Trcek T, et al. (2011) Single-molecule mRNA decay measurements reveal promoter- regulated mRNA stability in yeast. Cell 147(7):1484-97 SGD PMID 22196726
  4. Visintin R and Amon A (2001) Regulation of the mitotic exit protein kinases Cdc15 and Dbf2. Mol Biol Cell 12(10):2961-74 SGD PMID 11598184
  5. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  6. submitted by Jeff Ubersax on 2004-01-27

See Help:Categories on how to add the wiki page for this gene to a Category </protect>