YDR078C

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Systematic name YDR078C
Gene name SHU2
Aliases
Feature type ORF, Verified
Coordinates Chr IV:602869..602198
Primary SGDID S000002485


Description of YDR078C: Component of the Shu complex, which promotes error-free DNA repair; Shu complex mediates inhibition of Srs2p function[1][2][3][4][5]




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References

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  1. Ball LG, et al. (2009) The yeast Shu complex couples error-free post-replication repair to homologous recombination. Mol Microbiol 73(1):89-102 SGD PMID 19496932
  2. Bernstein KA, et al. (2011) The Shu complex, which contains Rad51 paralogues, promotes DNA repair through inhibition of the Srs2 anti-recombinase. Mol Biol Cell 22(9):1599-607 SGD PMID 21372173
  3. Huang ME, et al. (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A 100(20):11529-34 SGD PMID 12972632
  4. Mankouri HW, et al. (2007) Shu proteins promote the formation of homologous recombination intermediates that are processed by sgs1-rmi1-top3. Mol Biol Cell 18(10):4062-73 SGD PMID 17671161
  5. Shor E, et al. (2005) A genetic screen for top3 suppressors in Saccharomyces cerevisiae identifies SHU1, SHU2, PSY3 and CSM2: four genes involved in error-free DNA repair. Genetics 169(3):1275-89 SGD PMID 15654096

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