YDR017C

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Systematic name YDR017C
Gene name KCS1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:482267..479115
Primary SGDID S000002424


Description of YDR017C: Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of high energy inositol pyrophosphates by Kcs1p is required for many processes such as vacuolar biogenesis, stress response and telomere maintenance[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [5] [6]




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References

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  1. Bennett M, et al. (2006) Inositol pyrophosphates: metabolism and signaling. Cell Mol Life Sci 63(5):552-64 SGD PMID 16429326
  2. Dubois E, et al. (2002) In Saccharomyces cerevisiae, the inositol polyphosphate kinase activity of Kcs1p is required for resistance to salt stress, cell wall integrity, and vacuolar morphogenesis. J Biol Chem 277(26):23755-63 SGD PMID 11956213
  3. Mulugu S, et al. (2007) A conserved family of enzymes that phosphorylate inositol hexakisphosphate. Science 316(5821):106-9 SGD PMID 17412958
  4. Saiardi A, et al. (2000) The inositol hexakisphosphate kinase family. Catalytic flexibility and function in yeast vacuole biogenesis. J Biol Chem 275(32):24686-92 SGD PMID 10827188
  5. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. submitted by Viktor Boer on 2003-07-25

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