YDL007W

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Systematic name YDL007W
Gene name RPT2
Aliases YHS4, YTA5
Feature type ORF, Verified
Coordinates Chr IV:438047..439360
Primary SGDID S000002165


Description of YDL007W: One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle[1][2][3]




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References

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  1. Glickman MH, et al. (1998) The regulatory particle of the Saccharomyces cerevisiae proteasome. Mol Cell Biol 18(6):3149-62 SGD PMID 9584156
  2. Glickman MH, et al. (1999) Functional analysis of the proteasome regulatory particle. Mol Biol Rep 26(1-2):21-8 SGD PMID 10363642
  3. Rubin DM, et al. (1998) Active site mutants in the six regulatory particle ATPases reveal multiple roles for ATP in the proteasome. EMBO J 17(17):4909-19 SGD PMID 9724628

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