YFR053C

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Systematic name YFR053C
Gene name HXK1
Aliases
Feature type ORF, Verified
Coordinates Chr VI:255049..253592
Primary SGDID S000001949


Description of YFR053C: Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p[1][2]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in sulfur limited chemostat cultures versus sulfur excess. [3] [4]


Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [3] [4]





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References

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  1. Lobo Z and Maitra PK (1977) Physiological role of glucose-phosphorylating enzymes in Saccharomyces cerevisiae. Arch Biochem Biophys 182(2):639-45 SGD PMID 332086
  2. Rodriguez A, et al. (2001) The hexokinase 2 protein regulates the expression of the GLK1, HXK1 and HXK2 genes of Saccharomyces cerevisiae. Biochem J 355(Pt 3):625-31 SGD PMID 11311123
  3. 3.0 3.1 Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  4. 4.0 4.1 submitted by Viktor Boer on 2003-07-25

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