YER037W

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Systematic name YER037W
Gene name PHM8
Aliases
Feature type ORF, Verified
Coordinates Chr V:225889..226854
Primary SGDID S000000839


Description of YER037W: Lysophosphatidic acid (LPA) phosphatase involved in LPA hydrolysis in response to phosphate starvation; phosphatase activity is soluble and Mg2+ dependent; expression is induced by low phosphate levels and by inactivation of Pho85p[1][2][3]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in phosphorus limited chemostat cultures versus phosphorus excess. [4] [5]





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References

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  1. Gray NS, et al. (1998) Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors. Science 281(5376):533-8 SGD PMID 9677190
  2. Ogawa N, et al. (2000) New components of a system for phosphate accumulation and polyphosphate metabolism in Saccharomyces cerevisiae revealed by genomic expression analysis. Mol Biol Cell 11(12):4309-21 SGD PMID 11102525
  3. Reddy VS, et al. (2008) The Saccharomyces cerevisiae PHM8 Gene Encodes a Soluble Magnesium-dependent Lysophosphatidic Acid Phosphatase. J Biol Chem 283(14):8846-54 SGD PMID 18234677
  4. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  5. submitted by Viktor Boer on 2003-07-25

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