YEL052W

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Systematic name YEL052W
Gene name AFG1
Aliases
Feature type ORF, Verified
Coordinates Chr V:56571..58100
Primary SGDID S000000778


Description of YEL052W: Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domain[1][2][3]




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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Khalimonchuk O, et al. (2007) Evidence for a pro-oxidant intermediate in the assembly of cytochrome oxidase. J Biol Chem 282(24):17442-9 SGD PMID 17430883
  3. Lee YJ and Wickner RB (1992) AFG1, a new member of the SEC18-NSF, PAS1, CDC48-VCP, TBP family of ATPases. Yeast 8(9):787-90 SGD PMID 1441755

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