YCL044C

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Systematic name YCL044C
Gene name MGR1
Aliases
Feature type ORF, Verified
Coordinates Chr III:48364..47111
Primary SGDID S000000549


Description of YCL044C: Subunit of the mitochondrial (mt) i-AAA protease supercomplex, which degrades misfolded mitochondrial proteins; forms a subcomplex with Mgr3p that binds to substrates to facilitate proteolysis; required for growth of cells lacking mtDNA[1][2]




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References

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  1. Dunn CD, et al. (2006) A genomewide screen for petite-negative yeast strains yields a new subunit of the i-AAA protease complex. Mol Biol Cell 17(1):213-26 SGD PMID 16267274
  2. Dunn CD, et al. (2008) Mgr3p and Mgr1p are adaptors for the mitochondrial i-AAA protease complex. Mol Biol Cell 19(12):5387-97 SGD PMID 18843051

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