YLR347C
(Redirected from RSL1)
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| Systematic name | YLR347C |
| Gene name | KAP95 |
| Aliases | RSL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:826413..823828 |
| Primary SGDID | S000004339 |
Description of YLR347C: Karyopherin beta, forms a complex with Srp1p/Kap60p; interacts with nucleoporins to mediate nuclear import of NLS-containing cargo proteins via the nuclear pore complex; regulates PC biosynthesis; GDP-to-GTP exchange factor for Gsp1p[1][2][3][4][5]
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References
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- ↑ Aitchison JD, et al. (1996) Kap104p: a karyopherin involved in the nuclear transport of messenger RNA binding proteins. Science 274(5287):624-7 SGD PMID 8849456
- ↑ Enenkel C, et al. (1995) Identification of a yeast karyopherin heterodimer that targets import substrate to mammalian nuclear pore complexes. J Biol Chem 270(28):16499-502 SGD PMID 7622450
- ↑ Gilchrist D and Rexach M (2003) Molecular basis for the rapid dissociation of nuclear localization signals from karyopherin alpha in the nucleoplasm. J Biol Chem 278(51):51937-49 SGD PMID 14514698
- ↑ Lonhienne TG, et al. (2009) Importin-{beta} Is a GDP-to-GTP Exchange Factor of Ran: IMPLICATIONS FOR THE MECHANISM OF NUCLEAR IMPORT. J Biol Chem 284(34):22549-58 SGD PMID 19549784
- ↑ Mackinnon MA, et al. (2009) The kap60-kap95 karyopherin complex directly regulates phosphatidylcholine synthesis. J Biol Chem 284(11):7376-84 SGD PMID 19141610
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