YOR145C

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Systematic name YOR145C
Gene name PNO1
Aliases DIM2, RRP20
Feature type ORF, Verified
Coordinates Chr XV:606171..605347
Primary SGDID S000005671


Description of YOR145C: Essential nucleolar protein required for pre-18S rRNA processing, interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain[1][2][3][4]




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References

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  1. Grava S, et al. (2000) Functional analysis of six genes from chromosomes XIV and XV of Saccharomyces cerevisiae reveals YOR145c as an essential gene and YNL059c/ARP5 as a strain-dependent essential gene encoding nuclear proteins. Yeast 16(11):1025-33 SGD PMID 10923024
  2. Senapin S, et al. (2003) RRP20, a component of the 90S preribosome, is required for pre-18S rRNA processing in Saccharomyces cerevisiae. Nucleic Acids Res 31(10):2524-33 SGD PMID 12736301
  3. Tone Y and Toh-E A (2002) Nob1p is required for biogenesis of the 26S proteasome and degraded upon its maturation in Saccharomyces cerevisiae. Genes Dev 16(24):3142-57 SGD PMID 12502737
  4. Vanrobays E, et al. (2004) Dim2p, a KH-domain protein required for small ribosomal subunit synthesis. RNA 10(4):645-56 SGD PMID 15037774

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