YDR014W
(Redirected from RAD61)
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| Systematic name | YDR014W |
| Gene name | RAD61 |
| Aliases | WPL1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:474046..475989 |
| Primary SGDID | S000002421 |
Description of YDR014W: Subunit of a complex (Scc3p, Pds5p, Rad61p) that inhibits sister chromatid cohesion; inhibited by Eco1p-acetylated cohesin subunits Smc3p and Mcd1p; related to the human Wapl protein that controls the association of cohesin with chromatin[1][2][3][4]
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References
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- ↑ Kueng S, et al. (2006) Wapl controls the dynamic association of cohesin with chromatin. Cell 127(5):955-67 SGD PMID 17113138
- ↑ Rolef Ben-Shahar T, et al. (2008) Eco1-dependent cohesin acetylation during establishment of sister chromatid cohesion. Science 321(5888):563-6 SGD PMID 18653893
- ↑ Rowland BD, et al. (2009) Building sister chromatid cohesion: smc3 acetylation counteracts an antiestablishment activity. Mol Cell 33(6):763-74 SGD PMID 19328069
- ↑ Sutani T, et al. (2009) Budding yeast Wpl1(Rad61)-Pds5 complex counteracts sister chromatid cohesion-establishing reaction. Curr Biol 19(6):492-7 SGD PMID 19268589
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