YER013W

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Systematic name YER013W
Gene name PRP22
Aliases
Feature type ORF, Verified
Coordinates Chr V:178841..182278
Primary SGDID S000000815


Description of YER013W: DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes[1][2][3][4][5]




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References

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  1. McPheeters DS and Muhlenkamp P (2003) Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast. Mol Cell Biol 23(12):4174-86 SGD PMID 12773561
  2. Schwer B and Gross CH (1998) Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing. EMBO J 17(7):2086-94 SGD PMID 9524130
  3. Umen JG and Guthrie C (1995) The second catalytic step of pre-mRNA splicing. RNA 1(9):869-85 SGD PMID 8548652
  4. Wagner JD, et al. (1998) The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes. EMBO J 17(10):2926-37 SGD PMID 9582286
  5. de la Cruz J, et al. (1999) Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 24(5):192-8 SGD PMID 10322435

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