YER013W
(Redirected from PRP22)
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| Systematic name | YER013W |
| Gene name | PRP22 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr V:178841..182278 |
| Primary SGDID | S000000815 |
Description of YER013W: DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes[1][2][3][4][5]
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References
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- ↑ McPheeters DS and Muhlenkamp P (2003) Spatial organization of protein-RNA interactions in the branch site-3' splice site region during pre-mRNA splicing in yeast. Mol Cell Biol 23(12):4174-86 SGD PMID 12773561
- ↑ Schwer B and Gross CH (1998) Prp22, a DExH-box RNA helicase, plays two distinct roles in yeast pre-mRNA splicing. EMBO J 17(7):2086-94 SGD PMID 9524130
- ↑ Umen JG and Guthrie C (1995) The second catalytic step of pre-mRNA splicing. RNA 1(9):869-85 SGD PMID 8548652
- ↑ Wagner JD, et al. (1998) The DEAH-box protein PRP22 is an ATPase that mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes. EMBO J 17(10):2926-37 SGD PMID 9582286
- ↑ de la Cruz J, et al. (1999) Unwinding RNA in Saccharomyces cerevisiae: DEAD-box proteins and related families. Trends Biochem Sci 24(5):192-8 SGD PMID 10322435
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