YDL134C

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Systematic name YDL134C
Gene name PPH21
Aliases PPH1
Feature type ORF, Verified
Coordinates Chr IV:220771..219662
Primary SGDID S000002292


Description of YDL134C: Catalytic subunit of protein phosphatase 2A (PP2A), functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis[1][2][3][4]




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References

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  1. Lin FC and Arndt KT (1995) The role of Saccharomyces cerevisiae type 2A phosphatase in the actin cytoskeleton and in entry into mitosis. EMBO J 14(12):2745-59 SGD PMID 7796803
  2. Sneddon AA, et al. (1990) Saccharomyces cerevisiae protein phosphatase 2A performs an essential cellular function and is encoded by two genes. EMBO J 9(13):4339-46 SGD PMID 2176150
  3. Wei H, et al. (2001) Carboxymethylation of the PP2A catalytic subunit in Saccharomyces cerevisiae is required for efficient interaction with the B-type subunits Cdc55p and Rts1p. J Biol Chem 276(2):1570-7 SGD PMID 11038366
  4. Zabrocki P, et al. (2002) Protein phosphatase 2A on track for nutrient-induced signalling in yeast. Mol Microbiol 43(4):835-42 SGD PMID 11929536

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