YMR129W

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Systematic name YMR129W
Gene name POM152
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:527804..531817
Primary SGDID S000004736


Description of YMR129W: Glycoprotein subunit of the transmembrane ring of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport, NPC biogenesis and spindle pole body duplication; homologous to human NUP210[1][2][3][4][5][6]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [7] [8]





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References

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  1. Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 SGD PMID 19524430
  2. Onischenko E, et al. (2009) Role of the Ndc1 interaction network in yeast nuclear pore complex assembly and maintenance. J Cell Biol 185(3):475-91 SGD PMID 19414609
  3. Rout MP, et al. (2000) The yeast nuclear pore complex: composition, architecture, and transport mechanism. J Cell Biol 148(4):635-51 SGD PMID 10684247
  4. Strambio-de-Castillia C, et al. (1995) Isolation and characterization of nuclear envelopes from the yeast Saccharomyces. J Cell Biol 131(1):19-31 SGD PMID 7559775
  5. Witkin KL, et al. (2010) Changes in the Nuclear Envelope Environment Affect Spindle Pole Body Duplication in Saccharomyces cerevisiae. Genetics 186(3):867-83 SGD PMID 20713690
  6. Wozniak RW, et al. (1994) POM152 is an integral protein of the pore membrane domain of the yeast nuclear envelope. J Cell Biol 125(1):31-42 SGD PMID 8138573
  7. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  8. submitted by Jeff Ubersax on 2004-01-29

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