YDR228C
(Redirected from PCF11)
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| Systematic name | YDR228C |
| Gene name | PCF11 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:923806..921926 |
| Primary SGDID | S000002636 |
Description of YDR228C: mRNA 3' end processing factor, essential component of cleavage and polyadenylation factor IA (CF IA), involved in pre-mRNA 3' end processing and in transcription termination; binds C-terminal domain of largest subunit of RNA pol II (Rpo21p); required for gene looping[1][2][3][4][5][6]
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References
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- ↑ Amrani N, et al. (1997) PCF11 encodes a third protein component of yeast cleavage and polyadenylation factor I. Mol Cell Biol 17(3):1102-9 SGD PMID 9032237
- ↑ Barilla D, et al. (2001) Cleavage/polyadenylation factor IA associates with the carboxyl-terminal domain of RNA polymerase II in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 98(2):445-50 SGD PMID 11149954
- ↑ Birse CE, et al. (1998) Coupling termination of transcription to messenger RNA maturation in yeast. Science 280(5361):298-301 SGD PMID 9535662
- ↑ Medler S, et al. (2011) Evidence for a complex of TFIIB with poly(A) polymerase and cleavage factor 1 subunits required for gene looping. J Biol Chem () SGD PMID 21835917
- ↑ Sadowski M, et al. (2003) Independent functions of yeast Pcf11p in pre-mRNA 3' end processing and in transcription termination. EMBO J 22(9):2167-77 SGD PMID 12727883
- ↑ de Vries H, et al. (2000) Human pre-mRNA cleavage factor II(m) contains homologs of yeast proteins and bridges two other cleavage factors. EMBO J 19(21):5895-904 SGD PMID 11060040
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