YMR273C

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Systematic name YMR273C
Gene name ZDS1
Aliases CES1, CKM1, NRC1, OSS1
Feature type ORF, Verified
Coordinates Chr XIII:813980..811233
Primary SGDID S000004886


Description of YMR273C: Protein with a role in regulating Swe1p-dependent polarized growth; involved in maintaining Cdc55p in the cytoplasm where it promotes mitotic entry; involved in mitotic exit through Cdc14p regulation; interacts with silencing proteins at the telomere; has a role in Bcy1p localization; implicated in mRNA nuclear export[1][2][3][4][5][6][7]




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References

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  1. Bi E and Pringle JR (1996) ZDS1 and ZDS2, genes whose products may regulate Cdc42p in Saccharomyces cerevisiae. Mol Cell Biol 16(10):5264-75 SGD PMID 8816439
  2. Estruch F, et al. (2005) Physical and genetic interactions link the yeast protein Zds1p with mRNA nuclear export. J Biol Chem 280(10):9691-7 SGD PMID 15619606
  3. Griffioen G, et al. (2001) Nucleocytoplasmic distribution of budding yeast protein kinase A regulatory subunit Bcy1 requires Zds1 and is regulated by Yak1-dependent phosphorylation of its targeting domain. Mol Cell Biol 21(2):511-23 SGD PMID 11134339
  4. Queralt E and Uhlmann F (2008) Separase cooperates with Zds1 and Zds2 to activate Cdc14 phosphatase in early anaphase. J Cell Biol 182(5):873-83 SGD PMID 18762578
  5. Rossio V and Yoshida S (2011) Spatial regulation of Cdc55-PP2A by Zds1/Zds2 controls mitotic entry and mitotic exit in budding yeast. J Cell Biol 193(3):445-54 SGD PMID 21536748
  6. Roy N and Runge KW (1999) The ZDS1 and ZDS2 proteins require the Sir3p component of yeast silent chromatin to enhance the stability of short linear centromeric plasmids. Chromosoma 108(3):146-61 SGD PMID 10398844
  7. Yasutis K, et al. (2010) Zds2p Regulates Swe1p-dependent Polarized Cell Growth in Saccharomyces cerevisiae via a Novel Cdc55p Interaction Domain. Mol Biol Cell 21(24):4373-86 SGD PMID 20980617

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