YNL036W

From SGD-Wiki
(Redirected from NCE3)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YNL036W
Gene name NCE103
Aliases NCE3
Feature type ORF, Verified
Coordinates Chr XIV:559814..560479
Primary SGDID S000004981


Description of YNL036W: Carbonic anhydrase; metalloenzyme that catalyzes CO2 hydration to bicarbonate, which is an important metabolic substrate, and protons; not expressed under conditions of high CO2, such as inside a growing colony, but transcription is induced in response to low CO2 levels, such as on the colony surface in ambient air; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; mutation affects non-classical protein export pathway[1][2][3][4][5]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Clark D, et al. (2004) Complementation of the yeast deletion mutant DeltaNCE103 by members of the beta class of carbonic anhydrases is dependent on carbonic anhydrase activity rather than on antioxidant activity. Biochem J 379(Pt 3):609-15 SGD PMID 15096093
  2. Cleves AE, et al. (1996) A new pathway for protein export in Saccharomyces cerevisiae. J Cell Biol 133(5):1017-26 SGD PMID 8655575
  3. Cottier F, et al. (2012) The bZIP Transcription Factor Rca1p Is a Central Regulator of a Novel CO(2) Sensing Pathway in Yeast. PLoS Pathog 8(1):e1002485 SGD PMID 22253597
  4. Gotz R, et al. (1999) Deletion of the carbonic anhydrase-like gene NCE103 of the yeast Saccharomyces cerevisiae causes an oxygen-sensitive growth defect. Yeast 15(10A):855-64 SGD PMID 10407265
  5. Supuran CT (2010) Carbonic anhydrase inhibition/activation: trip of a scientist around the world in the search of novel chemotypes and drug targets. Curr Pharm Des 16(29):3233-45 SGD PMID 20819070

See Help:Categories on how to add the wiki page for this gene to a Category </protect>