YDR277C
(Redirected from MTH1)
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| Systematic name | YDR277C |
| Gene name | MTH1 |
| Aliases | BPC1, DGT1, HTR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1015702..1014401 |
| Primary SGDID | S000002685 |
Description of YDR277C: Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation[1][2][3]
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References
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- ↑ Lafuente MJ, et al. (2000) Mth1 receives the signal given by the glucose sensors Snf3 and Rgt2 in Saccharomyces cerevisiae. Mol Microbiol 35(1):161-72 SGD PMID 10632886
- ↑ Lakshmanan J, et al. (2003) Repression of transcription by Rgt1 in the absence of glucose requires Std1 and Mth1. Curr Genet 44(1):19-25 SGD PMID 14508605
- ↑ Moriya H and Johnston M (2004) Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I. Proc Natl Acad Sci U S A 101(6):1572-7 SGD PMID 14755054
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