YDR277C

From SGD-Wiki
(Redirected from MTH1)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YDR277C
Gene name MTH1
Aliases BPC1, DGT1, HTR1
Feature type ORF, Verified
Coordinates Chr IV:1015702..1014401
Primary SGDID S000002685


Description of YDR277C: Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation[1][2][3]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Lafuente MJ, et al. (2000) Mth1 receives the signal given by the glucose sensors Snf3 and Rgt2 in Saccharomyces cerevisiae. Mol Microbiol 35(1):161-72 SGD PMID 10632886
  2. Lakshmanan J, et al. (2003) Repression of transcription by Rgt1 in the absence of glucose requires Std1 and Mth1. Curr Genet 44(1):19-25 SGD PMID 14508605
  3. Moriya H and Johnston M (2004) Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I. Proc Natl Acad Sci U S A 101(6):1572-7 SGD PMID 14755054

See Help:Categories on how to add the wiki page for this gene to a Category </protect>