YOR370C

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Systematic name YOR370C
Gene name MRS6
Aliases MSI4
Feature type ORF, Verified
Coordinates Chr XV:1030994..1029183
Primary SGDID S000005897


Description of YOR370C: Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p); sequence similarity to mammalian choroideraemia gene[1][2][3][4]




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References

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  1. Benito-Moreno RM, et al. (1994) Mrs6p, the yeast homologue of the mammalian choroideraemia protein: immunological evidence for its function as the Ypt1p Rab escort protein. Curr Genet 27(1):23-5 SGD PMID 7750142
  2. Miaczynska M, et al. (1997) The yeast Rab escort protein binds intracellular membranes in vivo and in vitro. J Biol Chem 272(27):16972-7 SGD PMID 9202009
  3. Waldherr M, et al. (1993) MRS6--yeast homologue of the choroideraemia gene. Nat Genet 3(3):193-4 SGD PMID 8387377
  4. Witter DJ and Poulter CD (1996) Yeast geranylgeranyltransferase type-II: steady state kinetic studies of the recombinant enzyme. Biochemistry 35(32):10454-63 SGD PMID 8756702

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