YCL057C-A

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Systematic name YCL057C-A
Gene name MOS1
Aliases MCS10, MIO10
Feature type ORF, Verified
Coordinates Chr III:24325..24032
Primary SGDID S000007547


Description of YCL057C-A: Mitochondrial protein essential for proper inner membrane organization; conserved component of the mitochondrial inner membrane organizing system (MICOS, MINOS, or MitOS), a scaffold-like structure on the intermembrane space side of the inner membrane which has a role in the maintenance of crista junctions and inner membrane architecture; ortholog of human MINOS1[1][2][3][4]




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References

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  1. Alkhaja AK, et al. (2011) MINOS1 is a conserved component of Mitofilin complexes and required for mitochondrial function and cristae organization. Mol Biol Cell () SGD PMID 22114354
  2. Harner M, et al. (2011) The mitochondrial contact site complex, a determinant of mitochondrial architecture.LID - 10.1038/emboj.2011.379 [doi] EMBO J () SGD PMID 22009199
  3. Hoppins S, et al. (2011) A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria. J Cell Biol () SGD PMID 21987634
  4. von der Malsburg K, et al. (2011) Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis. Dev Cell () SGD PMID 21944719

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