YDL128W
(Redirected from MNR1)
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| Systematic name | YDL128W |
| Gene name | VCX1 |
| Aliases | HUM1, MNR1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:232652..233887 |
| Primary SGDID | S000002286 |
Description of YDL128W: Vacuolar membrane antiporter with Ca2+/H+ and K+/H+ exchange activity, involved in control of cytosolic Ca2+ and K+ concentrations; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter[1][2][3][4]
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References
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- ↑ Cagnac O, et al. (2010) Vacuolar cation/H+ antiporters of Saccharomyces cerevisiae. J Biol Chem 285(44):33914-22 SGD PMID 20709757
- ↑ Cunningham KW and Fink GR (1996) Calcineurin inhibits VCX1-dependent H+/Ca2+ exchange and induces Ca2+ ATPases in Saccharomyces cerevisiae. Mol Cell Biol 16(5):2226-37 SGD PMID 8628289
- ↑ Miseta A, et al. (1999) The vacuolar Ca2+/H+ exchanger Vcx1p/Hum1p tightly controls cytosolic Ca2+ levels in S. cerevisiae. FEBS Lett 451(2):132-6 SGD PMID 10371152
- ↑ Pozos TC, et al. (1996) The product of HUM1, a novel yeast gene, is required for vacuolar Ca2+/H+ exchange and is related to mammalian Na+/Ca2+ exchangers. Mol Cell Biol 16(7):3730-41 SGD PMID 8668190
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