YGL251C

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Systematic name YGL251C
Gene name HFM1
Aliases MER3
Feature type ORF, Verified
Coordinates Chr VII:31636..27921
Primary SGDID S000003220


Description of YGL251C: Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity[1][2][3][4]




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References

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  1. Coissac E, et al. (1996) Sequence of a 39,411 bp DNA fragment covering the left end of chromosome VII of Saccharomyces cerevisiae. Yeast 12(15):1555-62 SGD PMID 8972578
  2. Nakagawa T and Kolodner RD (2002) Saccharomyces cerevisiae Mer3 is a DNA helicase involved in meiotic crossing over. Mol Cell Biol 22(10):3281-91 SGD PMID 11971962
  3. Nakagawa T and Kolodner RD (2002) The MER3 DNA helicase catalyzes the unwinding of holliday junctions. J Biol Chem 277(31):28019-24 SGD PMID 12039965
  4. Nakagawa T, et al. (2001) The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction. J Biol Chem 276(34):31487-93 SGD PMID 11376001

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