YHR058C
(Redirected from MED6)
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Systematic name | YHR058C |
Gene name | MED6 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr VIII:219884..218997 |
Primary SGDID | S000001100 |
Description of YHR058C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation[1][2][3][4]
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References
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- ↑ Guglielmi B, et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32(18):5379-91 SGD PMID 15477388
- ↑ Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
- ↑ Lee YC, et al. (1997) A transcriptional mediator protein that is required for activation of many RNA polymerase II promoters and is conserved from yeast to humans. Mol Cell Biol 17(8):4622-32 SGD PMID 9234719
- ↑ Myers LC, et al. (1998) The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev 12(1):45-54 SGD PMID 9420330
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