YDR308C
(Redirected from MED21)
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| Systematic name | YDR308C |
| Gene name | SRB7 |
| Aliases | MED21 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:1078449..1078027 |
| Primary SGDID | S000002716 |
Description of YDR308C: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p[1][2][3]
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References
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- ↑ Gromoller A and Lehming N (2000) Srb7p is a physical and physiological target of Tup1p. EMBO J 19(24):6845-52 SGD PMID 11118219
- ↑ Hengartner CJ, et al. (1995) Association of an activator with an RNA polymerase II holoenzyme. Genes Dev 9(8):897-910 SGD PMID 7774808
- ↑ Kornberg RD (2005) Mediator and the mechanism of transcriptional activation. Trends Biochem Sci 30(5):235-9 SGD PMID 15896740
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