YOL051W
(Redirected from MED15)
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| Systematic name | YOL051W |
| Gene name | GAL11 |
| Aliases | ABE1, MED15, RAR3, SDS4, SPT13 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:234940..238185 |
| Primary SGDID | S000005411 |
Description of YOL051W: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors; forms part of the tail domain of mediator[1][2][3][4][5]
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References
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- ↑ Guglielmi B, et al. (2004) A high resolution protein interaction map of the yeast Mediator complex. Nucleic Acids Res 32(18):5379-91 SGD PMID 15477388
- ↑ Han SJ, et al. (2001) Med9/Cse2 and Gal11 modules are required for transcriptional repression of distinct group of genes. J Biol Chem 276(40):37020-6 SGD PMID 11470794
- ↑ Li Y, et al. (1995) Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme. Proc Natl Acad Sci U S A 92(24):10864-8 SGD PMID 7479899
- ↑ Mizuno T and Harashima S (2003) Gal11 is a general activator of basal transcription, whose activity is regulated by the general repressor Sin4 in yeast. Mol Genet Genomics 269(1):68-77 SGD PMID 12715155
- ↑ Myers LC and Kornberg RD (2000) Mediator of transcriptional regulation. Annu Rev Biochem 69():729-49 SGD PMID 10966474
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