YIL065C

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Systematic name YIL065C
Gene name FIS1
Aliases MDV2
Feature type ORF, Verified
Coordinates Chr IX:241775..241308
Primary SGDID S000001327


Description of YIL065C: Protein involved in mitochondrial membrane fission and peroxisome abundance; required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation[1][2][3]




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References

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  1. Kitagaki H, et al. (2007) Ethanol-induced death in yeast exhibits features of apoptosis mediated by mitochondrial fission pathway. FEBS Lett 581(16):2935-42 SGD PMID 17544409
  2. Kuravi K, et al. (2006) Dynamin-related proteins Vps1p and Dnm1p control peroxisome abundance in Saccharomyces cerevisiae. J Cell Sci 119(Pt 19):3994-4001 SGD PMID 16968746
  3. Mozdy AD, et al. (2000) Dnm1p GTPase-mediated mitochondrial fission is a multi-step process requiring the novel integral membrane component Fis1p. J Cell Biol 151(2):367-80 SGD PMID 11038183

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