YLL019C
(Redirected from L124)
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| Systematic name | YLL019C |
| Gene name | KNS1 |
| Aliases | L124 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:107899..105686 |
| Primary SGDID | S000003942 |
Description of YLL019C: Protein kinase involved in negative regulation of PolIII transcription; effector kinase of the TOR signaling pathway and phosphorylates Rpc53p to regulate ribosome and tRNA biosynthesis; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues; capable of autophosphorylation[1][2][3]
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References
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- ↑ Lee J, et al. (2012) TOR Signaling Regulates Ribosome and tRNA Synthesis via LAMMER/Clk and GSK-3 Family Kinases. Mol Cell () SGD PMID 22364741
- ↑ Lee K, et al. (1996) Activity and autophosphorylation of LAMMER protein kinases. J Biol Chem 271(44):27299-303 SGD PMID 8910305
- ↑ Padmanabha R, et al. (1991) The KNS1 gene of Saccharomyces cerevisiae encodes a nonessential protein kinase homologue that is distantly related to members of the CDC28/cdc2 gene family. Mol Gen Genet 229(1):1-9 SGD PMID 1910150
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