YDL216C
(Redirected from JAB1)
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| Systematic name | YDL216C |
| Gene name | RRI1 |
| Aliases | CSN5, JAB1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:70319..68997 |
| Primary SGDID | S000002375 |
Description of YDL216C: Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling[1][2][3]
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References
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- ↑ Cope GA, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298(5593):608-11 SGD PMID 12183637
- ↑ Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 SGD PMID 12446563
- ↑ Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 SGD PMID 12186635
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