YDL216C

From SGD-Wiki
(Redirected from JAB1)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YDL216C
Gene name RRI1
Aliases CSN5, JAB1
Feature type ORF, Verified
Coordinates Chr IV:70319..68997
Primary SGDID S000002375


Description of YDL216C: Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling[1][2][3]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Cope GA, et al. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cul1. Science 298(5593):608-11 SGD PMID 12183637
  2. Maytal-Kivity V, et al. (2002) COP9 signalosome components play a role in the mating pheromone response of S. cerevisiae. EMBO Rep 3(12):1215-21 SGD PMID 12446563
  3. Wee S, et al. (2002) Conservation of the COP9/signalosome in budding yeast. BMC Genet 3():15 SGD PMID 12186635

See Help:Categories on how to add the wiki page for this gene to a Category </protect>