YPR133C
(Redirected from IWS1)
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| Systematic name | YPR133C |
| Gene name | SPN1 |
| Aliases | IWS1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:797210..795978 |
| Primary SGDID | S000006337 |
Description of YPR133C: Protein involved in RNA polymerase II transcription; interacts genetically or physically with RNAP II, TBP, TFIIS, and chromatin remodelling factors; central domain highly conserved throughout eukaryotes; mutations confer an Spt- phenotype[1][2][3][4]
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References
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- ↑ Fischbeck JA, et al. (2002) SPN1, a conserved gene identified by suppression of a postrecruitment-defective yeast TATA-binding protein mutant. Genetics 162(4):1605-16 SGD PMID 12524336
- ↑ Krogan NJ, et al. (2002) RNA polymerase II elongation factors of Saccharomyces cerevisiae: a targeted proteomics approach. Mol Cell Biol 22(20):6979-92 SGD PMID 12242279
- ↑ Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 SGD PMID 12556496
- ↑ Pujari V, et al. (2010) The Transcription Factor Spn1 Regulates Gene Expression via a Highly Conserved Novel Structural Motif. J Mol Biol 404(1):1-15 SGD PMID 20875428
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