YJL154C
(Redirected from GRD9)
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| Systematic name | YJL154C |
| Gene name | VPS35 |
| Aliases | GRD9, VPT7 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:133935..131101 |
| Primary SGDID | S000003690 |
Description of YJL154C: Endosomal subunit of membrane-associated retromer complex required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval; interacts with Ypt7p[1][2][3][4][5]
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References
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- ↑ Liu TT, et al. (2012) Rab GTPase regulation of retromer-mediated cargo export during endosome maturation. Mol Biol Cell 23(13):2505-15 SGD PMID 22593205
- ↑ Nothwehr SF, et al. (1996) The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol Cell Biol 16(6):2700-7 SGD PMID 8649377
- ↑ Nothwehr SF, et al. (2000) Sorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35p. J Cell Biol 151(2):297-310 SGD PMID 11038177
- ↑ Reddy JV and Seaman MN (2001) Vps26p, a component of retromer, directs the interactions of Vps35p in endosome-to-Golgi retrieval. Mol Biol Cell 12(10):3242-56 SGD PMID 11598206
- ↑ Seaman MN, et al. (1998) A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast. J Cell Biol 142(3):665-81 SGD PMID 9700157
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