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Systematic name YKR001C
Gene name VPS1
Aliases GRD1, LAM1, SPO15, VPL1, VPT26
Feature type ORF, Verified
Coordinates Chr XI:442722..440608
Primary SGDID S000001709

Description of YKR001C: Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization, endocytosis, late Golgi-retention of some proteins, regulation of peroxisome biogenesis[1][2][3][4][5]


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  1. Ekena K, et al. (1993) The VPS1 protein is a dynamin-like GTPase required for sorting proteins to the yeast vacuole. Ciba Found Symp 176():198-211; discussion 211-4 SGD PMID 8299420
  2. Nothwehr SF, et al. (1996) The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol Cell Biol 16(6):2700-7 SGD PMID 8649377
  3. Rooij II, et al. (2010) A role for the dynamin-like protein Vps1 during endocytosis in yeast. J Cell Sci 123(Pt 20):3496-506 SGD PMID 20841380
  4. Vizeacoumar FJ, et al. (2003) YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae. J Cell Biol 161(2):321-32 SGD PMID 12707309
  5. Yu X and Cai M (2004) The yeast dynamin-related GTPase Vps1p functions in the organization of the actin cytoskeleton via interaction with Sla1p. J Cell Sci 117(Pt 17):3839-53 SGD PMID 15265985

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