YDR508C

From SGD-Wiki
(Redirected from GNP1)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YDR508C
Gene name GNP1
Aliases
Feature type ORF, Verified
Coordinates Chr IV:1468444..1466453
Primary SGDID S000002916


Description of YDR508C: High-affinity glutamine permease; also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids; GNP1 has a paralog, AGP1, that arose from the whole genome duplication[1][2][3][4][5]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!

DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically higher expression in sulfur limited chemostat cultures versus sulfur excess. [6] [7]


Other Topic: expression

Specifically lower expression in nitrogen limited chemostat cultures versus nitrogen excess. [6] [7]





<protect>

References

See Help:References on how to add references

  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Eckert-Boulet N, et al. (2005) Grr1p is required for transcriptional induction of amino acid permease genes and proper transcriptional regulation of genes in carbon metabolism of Saccharomyces cerevisiae. Curr Genet 47(3):139-49 SGD PMID 15611869
  3. Forsberg H, et al. (2001) The role of the yeast plasma membrane SPS nutrient sensor in the metabolic response to extracellular amino acids. Mol Microbiol 42(1):215-28 SGD PMID 11679080
  4. Regenberg B, et al. (1999) Substrate specificity and gene expression of the amino-acid permeases in Saccharomyces cerevisiae. Curr Genet 36(6):317-28 SGD PMID 10654085
  5. Zhu X, et al. (1996) GNP1, the high-affinity glutamine permease of S. cerevisiae. Curr Genet 30(2):107-14 SGD PMID 8660458
  6. 6.0 6.1 Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  7. 7.0 7.1 submitted by Viktor Boer on 2003-07-25

See Help:Categories on how to add the wiki page for this gene to a Category </protect>