YOR375C
(Redirected from GDH1)
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| Systematic name | YOR375C |
| Gene name | GDH1 |
| Aliases | DHE4, GDH-A, GDHA, URE1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:1043042..1041678 |
| Primary SGDID | S000005902 |
Description of YOR375C: NADP(+)-dependent glutamate dehydrogenase; synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources; GDH1 has a paralog, GDH3, that arose from the whole genome duplication[1][2][3]
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References
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- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ DeLuna A, et al. (2001) NADP-glutamate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, kinetic properties, and physiological roles. J Biol Chem 276(47):43775-83 SGD PMID 11562373
- ↑ Riego L, et al. (2002) GDH1 expression is regulated by GLN3, GCN4, and HAP4 under respiratory growth. Biochem Biophys Res Commun 293(1):79-85 SGD PMID 12054566
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