YDL215C

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Systematic name YDL215C
Gene name GDH2
Aliases GDH-B, GDHB
Feature type ORF, Verified
Coordinates Chr IV:73918..70640
Primary SGDID S000002374


Description of YDL215C: NAD(+)-dependent glutamate dehydrogenase, degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels[1][2][3]




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References

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  1. DeLuna A, et al. (2001) NADP-glutamate dehydrogenase isoenzymes of Saccharomyces cerevisiae. Purification, kinetic properties, and physiological roles. J Biol Chem 276(47):43775-83 SGD PMID 11562373
  2. Miller SM and Magasanik B (1990) Role of NAD-linked glutamate dehydrogenase in nitrogen metabolism in Saccharomyces cerevisiae. J Bacteriol 172(9):4927-35 SGD PMID 1975578
  3. Tate JJ and Cooper TG (2003) Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism. J Biol Chem 278(38):36924-33 SGD PMID 12851403

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