YAL002W

From SGD-Wiki
(Redirected from FUN15)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YAL002W
Gene name VPS8
Aliases FUN15, VPL8, VPT8
Feature type ORF, Verified
Coordinates Chr I:143707..147531
Primary SGDID S000000002


Description of YAL002W: Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif[1][2][3][4][5]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!



<protect>

References

See Help:References on how to add references

  1. Chen YJ and Stevens TH (1996) The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae. Eur J Cell Biol 70(4):289-97 SGD PMID 8864656
  2. Horazdovsky BF, et al. (1996) A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization. J Biol Chem 271(52):33607-15 SGD PMID 8969229
  3. Luo W and Chang A (1997) Novel genes involved in endosomal traffic in yeast revealed by suppression of a targeting-defective plasma membrane ATPase mutant. J Cell Biol 138(4):731-46 SGD PMID 9265642
  4. Markgraf DF, et al. (2009) The CORVET Subunit Vps8 Cooperates with the Rab5 Homolog Vps21 to Induce Clustering of Late Endosomal Compartments. Mol Biol Cell 20(24):5276-89 SGD PMID 19828734
  5. Peplowska K, et al. (2007) The CORVET Tethering Complex Interacts with the Yeast Rab5 Homolog Vps21 and Is Involved in Endo-Lysosomal Biogenesis. Dev Cell 12(5):739-50 SGD PMID 17488625

See Help:Categories on how to add the wiki page for this gene to a Category </protect>