YDR110W
(Redirected from FOB1)
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| Systematic name | YDR110W |
| Gene name | FOB1 |
| Aliases | HRM1 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:676102..677802 |
| Primary SGDID | S000002517 |
Description of YDR110W: Nucleolar protein that binds the rDNA replication fork barrier (RFB) site; required for replication fork blocking, recombinational hotspot activity, condensin recruitment to RFB and rDNA repeat segregation; related to retroviral integrases[1][2][3][4][5]
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References
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- ↑ Defossez PA, et al. (1999) Elimination of replication block protein Fob1 extends the life span of yeast mother cells. Mol Cell 3(4):447-55 SGD PMID 10230397
- ↑ Dlakic M (2002) A model of the replication fork blocking protein Fob1p based on the catalytic core domain of retroviral integrases. Protein Sci 11(5):1274-7 SGD PMID 11967383
- ↑ Johzuka K and Horiuchi T (2009) The cis element and factors required for condensin recruitment to chromosomes. Mol Cell 34(1):26-35 SGD PMID 19362534
- ↑ Kobayashi T (2003) The replication fork barrier site forms a unique structure with Fob1p and inhibits the replication fork. Mol Cell Biol 23(24):9178-88 SGD PMID 14645529
- ↑ Kobayashi T and Horiuchi T (1996) A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1(5):465-74 SGD PMID 9078378
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