YJR093C

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Systematic name YJR093C
Gene name FIP1
Aliases
Feature type ORF, Verified
Coordinates Chr X:604203..603220
Primary SGDID S000003853


Description of YJR093C: Subunit of cleavage polyadenylation factor (CPF), interacts directly with poly(A) polymerase (Pap1p) to regulate its activity; bridging factor that links Pap1p and the CPF complex via Yth1p[1][2][3][4]




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References

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  1. Ezeokonkwo C, et al. (2011) A flexible linker region in Fip1 is needed for efficient mRNA polyadenylation. RNA 17(4):652-64 SGD PMID 21282348
  2. Gross S and Moore C (2001) Five subunits are required for reconstitution of the cleavage and polyadenylation activities of Saccharomyces cerevisiae cleavage factor I. Proc Natl Acad Sci U S A 98(11):6080-5 SGD PMID 11344258
  3. Helmling S, et al. (2001) Fip1 regulates the activity of Poly(A) polymerase through multiple interactions. Mol Cell Biol 21(6):2026-37 SGD PMID 11238938
  4. Preker PJ, et al. (1995) The FIP1 gene encodes a component of a yeast pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase. Cell 81(3):379-89 SGD PMID 7736590

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