YJL085W
(Redirected from EXO70)
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| Systematic name | YJL085W |
| Gene name | EXO70 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr X:272827..274698 |
| Primary SGDID | S000003621 |
Description of YJL085W: Subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which directs secretory vesicles to active sites of exocytosis; acts with Sec3p in membrane targeting of the exocyst via PI(4,5)P2 binding[1][2][3]
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References
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- ↑ He B, et al. (2007) Exo70 interacts with phospholipids and mediates the targeting of the exocyst to the plasma membrane. EMBO J 26(18):4053-65 SGD PMID 17717527
- ↑ Robinson NG, et al. (1999) Rho3 of Saccharomyces cerevisiae, which regulates the actin cytoskeleton and exocytosis, is a GTPase which interacts with Myo2 and Exo70. Mol Cell Biol 19(5):3580-7 SGD PMID 10207081
- ↑ TerBush DR, et al. (1996) The Exocyst is a multiprotein complex required for exocytosis in Saccharomyces cerevisiae. EMBO J 15(23):6483-94 SGD PMID 8978675
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