YLR172C

From SGD-Wiki
(Redirected from DPH5)
Jump to: navigation, search

Share your knowledge...Edit this entry! <protect>

Systematic name YLR172C
Gene name DPH5
Aliases
Feature type ORF, Verified
Coordinates Chr XII:502162..501260
Primary SGDID S000004162


Description of YLR172C: Methyltransferase required for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm[1][2][3]




</protect>

Community Commentary

About Community Commentary. Please share your knowledge!




<protect>

References

See Help:References on how to add references

  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Liu S, et al. (2004) Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol 24(21):9487-97 SGD PMID 15485916
  3. Mattheakis LC, et al. (1992) DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae. Mol Cell Biol 12(9):4026-37 SGD PMID 1508200

See Help:Categories on how to add the wiki page for this gene to a Category </protect>