YLR172C
(Redirected from DPH5)
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| Systematic name | YLR172C |
| Gene name | DPH5 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:502162..501260 |
| Primary SGDID | S000004162 |
Description of YLR172C: Methyltransferase required for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm[1][2][3]
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References
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- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Liu S, et al. (2004) Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. Mol Cell Biol 24(21):9487-97 SGD PMID 15485916
- ↑ Mattheakis LC, et al. (1992) DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae. Mol Cell Biol 12(9):4026-37 SGD PMID 1508200
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